Pre-Implantation Genetic Test (PGT)

What is PGT?

It is a diagnostic method that is performed on the embryo before it is transferred to the mother’s uterus to make sure it is not affected by any chromosome abnormalities or genetic mutations.

When there is a risk of passing on numerical chromosome abnormalities, structural abnormalities or serious hereditary conditions to offspring, PGT can inform us about each embryo’s status, thus allowing us to transfer only those embryos which do not present any of the abnormalities that were screened for.


Pre-Implantation Genetic Test


  • Illnesses that affect a single gene (dominant, recessive or X linked), whose mutation is known and can be analysed, X linked disorders whose gene is unknown or which are affected by some level of heterogeneity and structural chromosome abnormalities.
  • Advanced maternal age, as this factor increases the risk of chromosome abnormalities such as Down syndrome, for example.
  • Implantation failure with IVF cycles, in which the percentage of abnormal embryos can be as high as 70%.
  • Severe male factor infertility, which represents 9% of cases.
  • Other abnormalities such as the HLA haplotype (histocompatibility), and chromosome abnormalities in spermatozoids.

What is the PGT process like?

Obtención embriones test genético preimplantacional

Creation of embryos


Biopsia embrionaria test genético preimplantacional

Embryo biopsy

We extract one or two cells from the embryo

Análisis genético de test genético preimplantacional

Genetic analysis

To study the illness

Transferencia embrionaria test genético preimplantacional

Embryo transfer

Using embryos that are not affected by the illness.

First fertility visit is free

Request your first appointment cost-free at the clinic closest to you

Frequently asked questions about PGT

Can Down syndrome be avoided with PGT?

One of the applications of the Pre-Implantation Genetic Test is, precisely, to detect chromosome abnormalities, meaning that with this test it is possible to diagnose conditions such as Down syndrome.

Is it advisable to carry out PGT if I am 40 years old?

The recommendation depends on each patient’s case. Each case would need to be studied and assessed by a specialist.

Can an A-quality embryo present genetic abnormalities?

Embryo quality varies depending on morphology, but the quality assigned to an embryo does not provide any information regarding its genetic material. That’s why a good quality embryo could present chromosome abnormalities, while a poor quality embryo could be free from chromosome abnormalities.